Jul 05, 2020  
2019-2020 Undergraduate Catalog 
    
2019-2020 Undergraduate Catalog

CHEM 4220 Advance Organic Chemistry


Advanced organic chemistry is a senior level organic chemistry course, which will concentrate on modern synthetic methods and reaction mechanism with emphasis on organometallic chemistry and total synthesis. This course covers a broad range of topics in modern organic chemistry, including stereoselective Aldol reactions and olefination reactions (Evans Aldol reaction, Mukaiyama Aldol, HWE and Julia Olifination reaction) and functional group interconverstion by substitution reaction. The oxidation and reduction reaction will be covered from the catalytic aspect. Organometallic chemistry and transition metal catalysis will be introduced with the 18-electron rule and catalytic circle being emphasized. Polymer chemistry, green chemistry, multistep synthesis and organocatalysis will also be covered. The laboratory section focus on organic laboratory practices and techniques, the experiments are designed to familiarize students with stereochemistry, green chemistry, organometallic chemistry and multistep synthesis. TLC, Flash Column Chromatography, HPLC are used for separation and purification. IR, GC-MS, NMR, UV-VIS are used to characterize intermediates and products. Prerequisite(s): CHEM 2570  (Organic Chemistry I lecture and lab) and CHEM 2580  (Organic Chemistry II lecture and lab).
Credits: 4.0